［1］NOTHIAS J Y, MAJUMDER S, KANEKO K J, et al. Regulation of gene expression at the beginning of mammalian development［J］.J Biol Chem,1995,270(38):22077-22080.
［2］KANEKO K J, DEPAMPHILIS M L. Regulation of gene expression at the beginning of mammalian development and the TEAD family of transcription factors［J］.Dev Genet,1998,22(1):43-55.
［3］TADROS W, LIPSHITZ H D. The maternal-to-zygotic transition: a play in two acts［J］.Development, 2009,136(18):3033-3042.
［4］SHIN S W, TOKORO M, NISHIKAWA S, et al. Inhibition of the ubiquitin-proteasome system leads to delay of the onset of ZGA gene expression［J］.J Reprod Dev,2010,56(6):655-663.
［5］CHRISTIANS E, DAVIS A A, THOMAS S D, et al. Maternal effect of Hsf1 on reproductive success［J］. Nature, 2000,407(6805):693-694.
［6］WU X, VIVEIROS M M, EPPIG J J, et al. Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition［J］.Nat Genet,2003,33(2):187-191.
［7］RAMOS S B, STUMPO D J, KENNINGTON E A, et al.The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development［J］. Development,2004,131(9): 4883-4893.
［8］RANKIN T, SOYAL S, DEAN J. The mouse zona pellucida: folliculogenesis, fertility and pre-implantation development［J］.Mol Cell Endocrinol,2000,163(1-2):21-25.
［9］TONG Z B, GOLD L, PFEIFER K E, et al. Mater, a maternal effect gene required for early embryonic development in mice［J］.Nat Genet,2000,26(3):267-268.
［10］QIU J J, ZHANG W W, WU Z L, et al. Delay of ZGA initiation occurred in 2-cell blocked mouse embryos［J］. Cell Res,2003,13(3):179-185.
［11］NASR-ESFAHANI M H, AITKEN J R, JOHNSON M H. Hydrogen peroxide levels in mouse oocytes and early cleavage stage embryos developed in vitro or in vivo［J］.Development,1990,109(2):501-507.
［12］LEGGE M, SELLENS M H. Free radical scavengers ameliorate the 2-cell block in mouse embryo culture［J］. Hum Reprod,1991,6(6):841-846.
［13］张传领,刘春梅,陆彩玲,等.性未成熟雌性小鼠孕前砷暴露导致植入前胚胎体外发育阻滞［J］.中国生物化学与分子生物学报,2010,26(9):841-846.
ZHANG C L, LIU C M, LU C L, et al. In vitro developmental retardation of preimplantation embryos from sexually immature female mice by pregestational arsenic administration［J］. Chinese Journal of Biochemistry and Molecular Biology,2010,26(9):841-846. (in Chinese)
［14］邱佳菁,李逸平.“生存还是毁灭”,发育还是阻滞──小鼠早胚体外发育2-细胞阻滞产生机制初析［J］.生命科学, 2000,12(5):193-198.
QIU J J,LI Y P.“To be or not to be”,to develop or to be blocked──The mechanism of 2-cell block in the early mouse embryo cultured in vitro［J］. Chinese Bulletin of Life Sciences,2000, 12(5):193-198.(in Chinese)
［15］OU X H,LI S,WANG Z B,et al.Maternal insulin resistance causes oxidative stress and mitochondrial dysfunction in mouse oocytes［J］.Hum Reprod,2012,27(7):2130-2145.
［16］DAS S,CHATTOPADHYAY R,GHOSH S,et al.Reactive oxygen species level in follicular fluid—embryo quality marker in IVF?［J］.Hum Reprod,2006,21(9):2403-2407.
［17］AL-GUBORY K H,FOWLER P A,GARREL C.The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes［J］.Int J Biochem Cell Biol,2010,42(10): 1634-1650.
［18］LEGGE M,SELLENS M H.Free radical scavengers ameliorate the 2-cell block in mouse embryo culture［J］.Hum Reprod,1991,6(6):867-871.
［19］ALI A A,BILODEAU J F,SIRARD M A.Antioxidant requirements for bovine oocytes varies during in vitro maturation, fertilization and development［J］.Theriogenology, 2003,59(3-4):939-949.
［20］HUANG Y,TANG X,XIE W,et al.Vitamin C enhances in vitro and in vivo development of porcine somatic cell nuclear transfer embryos［J］. Biochem Biophys Res Commun,2011,411(2):397-401.
［21］POLVANI S,TAROCCHI M,GALLI A.PPARγ and oxidative stress: Con(β) catenating NRF2 and FOXO［J］.PPAR Res,2012,2012(2): 641087.
［22］COLLINS A R, LYON C J, XIA X, et al. Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes［J］. Circ Res,2009,104(6):42-54.
［23］PARK E Y, CHO I J, KIM S G. Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-γ and retinoid X receptor heterodimer［J］. Cancer Res,2004, 64(10):3701-3713.
［24］ISHII T, ITON K, RUIZ E, et al. Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal［J］.Circ Res,2004,94(5): 609-616.
［25］KOVAC S, ANGELOVA P R, HOLMSTRÖM K M, et al. Nrf2 regulates ROS production by mitochondria and NADPH oxidase［J］. Biochim Biophys Acta,2015,1850(4): 794-801.
［26］MARTÍN A, PÉREZ-GIRÓN J V, HERNANZ R, et al. Peroxisome proliferator-activated receptor -γ activation reduces cyclooxygenase-2 expression in vascular smooth muscle cells from hypertensive rats by interfering with oxidative stress［J］. J Hypertens, 2012,30(2): 315-326.
［27］MÄKELÄ J, TSELYKH T V, KUKKONEN J P, et al.Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons［J］. Neuropharmacology，2016,102:266-275.
［28］ZHOU Y,ZHANG M J,LI B H,et al.PPARγ inhibits VSMC proliferation and migration via attenuating oxidative stress through upregulating UCP2［J］.PLoS One,2016,11(5):e0154720.
［29］CHEN J, LI D, ZHANG X, et al.Tumor necrosis factor-alpha-induced apoptosis of human coronary artery endothelial cells: modulation by the peroxisome proliferator-activated receptor-gamma ligand pioglitazone［J］.J Cardiovasc Pharmacol Ther,2004,9(1):35-41.
［30］SCHINI S A, BAVISTER B D. Two-cell block to development of cultured hamster embryos is caused by phosphate and glucose［J］.Biol Reprod,1988,39(5):1183-1192.
［31］YANG P, ZHAO Z, REECE E A. Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy［J］.Am J Obstet Gynecol,2008,198(1):1-7.
［32］FLOOD J T, CHILLIK C F, VAN UEM J F, et al. Ooplasmic transfusion:prophase germinal vesicle oocytes made developmentally competent by microinjection of metaphase II egg cytoplasm［J］. Fertil Steril,1990,53(6):1049-1054.
［33］CHU D P, TIAN S, QI L, et al. Abnormality of maternal-to-embryonic transition contributes to MEHP-induced mouse 2-cell block［J］.J Cell Physiol,2013,228(4):753-763.
［34］ZHANG Y, JIANG Y, LIAN X，et al. Effects of ERα-specific antagonist on mouse preimplantation embryo development and zygotic genome activation［J］.J Steroid Biochem Mol Biol,2015,145: 13-20.